USDA Zone? Bulbine frutescens Bulbine frutescens 2 is a plant from South Africa that contains two substances proven to reduce the rate of collagen breakdown in your skin and increase collagen production. The leaves of the Bulbine frutescens are used in traditional medicine. The rewards program that helps you save on SkinMedica® and select Allergan products and services. However, the Bulbine frutescens extract unexpectedly strengthens the transdermal transport (even in nails), as demonstrated by tests with the Franz diffusion cell. The extract prepared as previously described was incorporated into the following topical formulation: The composition was applied to the feet of users with athlete's foot (six volunteers). The desired microbial freedom and freedom from pathogens can be achieved, for example, by working under sterile conditions, with sterile equipment, and using controlled starting materials. Complete kill after 1 hour. The effect is to some extent far superior to that of commercial products, and the natural microflora of the skin and mucous membranes is not damaged but instead remains intact. Bringmann et al. PORTER WRIGHT MORRIS & ARTHUR, LLP (COLUMBUS, OH, US), Click for automatic bibliography The flowers are yellow or orange and are borne on slender spikes from August through summer to June. Because of its hydration qualities, the active can be … The dosage of the Bulbine frutescens extract depends on, among other things, the dosage form, the intended purpose, the impairment to be treated, the disease or disorder, the user, the specifically selected vehicles and/or excipients. Complete kill after 1 hour. But in the near future it will become one of the best ground covers we have in central Florida. These products have not been approved by the FDA, and the statements have not been evaluated by the FDA. These resistant strains are usually difficult to control, in particular in a hospital environment. By way of example, a Bulbine frutescens extract may be produced by the following steps: The leaves of Bulbine frutescens can be harvested throughout the entire year, but the harvest is usually conducted at least twice. Three separate rat studies looking at … The efficacy is surprisingly high, even exceeding that of commercial products. It was found that applying the cream twice daily led to a 40% improvement in elasticity and an approximately 24% improvement in tensile strength of the skin, and water loss of the subcutaneous tissue to the environment was greatly reduced in proportion to the standard. Another health benefit provided by Bulbine Natalensis is to prevent bacterial infections. In some cases, hydrogen sulfide, methyl mercaptan and dimethyl sulfide make a significant contribution to mouth odor in addition to various alkylated amines. Its long bloom season make it particularly … Bulbine natalensis and Bulbine frutescens of the Asphodelaceae family are indigenous to only southern Africa and are widely used as a skin remedy. The Bulbine frutescens extract can therefore be used as a functional ingredient. The Bulbine frutescens extract is thus superior to traditional pharmaceutical preparations, including preparations for oral disinfection based on chlorhexidine gluconate and hydrogen peroxide. Scientifically Confirmed Effects: Stimulates the proliferation of fibroblasts (in-vitro study); Activates the production of high quality collagen (in-vitro study)Acts as collagen filler and lifting agent (in-vivo study)Reduces stretch marks and increases self esteem (in-vivo study)Provides fast results at a low concentration (in-vivo study)Repairs unsightly appearance of skin … I have now found that bulbine frutescens has important hydrating properties. Bulbine frutescens enables the restoration of skin barrier function, … It was found that the fungus microorganisms were completely eliminated after 35 days and no further relapses were observed after three months. It may also be desirable to protect the Bulbine frutescens extract that is prepared from opportunistic microorganisms. Since some polysaccharides have proven beneficial in wound healing, in vitro studies were conducted to determine the cytotoxicity and cell proliferation effects of the Bulbine frutescens extract. 65, 1117 (2002)) have described gaboroquinone A and B, 4′-O-demethylknipholone-4′-O-β-d-glucopyranoie and phenyl anthraquinones from the roots of Bulbine frutescens. These two compounds are Knipholone and Acetylated Polymannose (APM). A cream containing the following was prepared: Thus a Bulbine frutescens extract has been made available wherein the active ingredient is plant-based, and the extract can be used in both the therapeutic and cosmetic fields for application to the skin and mucous membranes, can be formulated in a variety of dosage forms and offers a broad spectrum of effects. The duration of hydrogen peroxide treatment is not particularly limited, but it may be desirable to adjust the treatment time to be as short as possible in order to avoid oxidative side reactions which would lead to discoloration. Test formulaons: Emulsion without Bulbine Frutescens Extract (placebo); Emulsion with 3 % Bulbine Frutescens … The extract was then incorporated into an antiperspirant formulation. This includes fungal diseases such as fungus infections of the feet and nails or candidiasis (including topical and vaginal candidiasis), injuries to the skin and mucous membranes such as burns and other types of wounds, and even furuncles and carbuncles. Jun 26, 2014 - Bulbine frutescens is native to South Africa and is similar to Iceplant with its fleshy, succulent green leaves. In the cosmetic field, the extract may be used for body care, oral care, as an antiperspirant and as an antiaging product. Bulbine frutescens 'Orange' SKU. In 1987, the fundamental compound 1,8 dihydroxyanthraquinone (Danthron®) was taken off the market throughout the world because of the well-founded suspicion that this compound is carcinogenic for humans. ETHNOPHARMACOLOGICAL RELEVANCE: The gel from the leaves of Bulbine natalensis (BN) and Bulbine frutescens (BF) is commonly used as a traditional medicine in South Africa for the treatment of skin wounds and burns. None were killed after 2 hours. The skin is amazingly self-sufficient. The efficacy of these agents is therefore very restricted. Pharmaceutically or cosmetically acceptable acids are selected, for example, from organic acids. (Chem. This test was also performed in accordance with the method of the American Society for Testing and Materials (ASTM) method E1174 using various inoculations. Use in the cosmetic field includes body care and beauty care, in other words, maintenance, restoration or improving the beauty of the human body, for example, by cleaning, stabilizing, moisturizing, vitalizing and/or deodorizing the skin and cleaning, stabilizing and/or vitalizing the mucous membranes. From April to August the plant bears yellow, orange or white blossoms in dense elongated flower clusters with a length of up to 30 cm and with a bearded stamen. Experiments in the Immunostimulating Properties of the Bulbine frutescens Extract, Wound Healing in Patients with a Weakened Immune System. The extract described herein may be used in the medical field, for example, in the treatment of diseases of the skin or mucous membranes, such as those associated with a microbiological cause, for example, due to opportunistic microorganisms or hypo/hyperactive enzymes. Extracts of bulbinella juice are used make a basis for skin creams and is used in the same way as Aloe vera. The following description of certain examples of the invention should not be used to limit the scope of the present invention. Bulbine frutescens is one of nature’s finest medicinal plants. Arabinogalactans are known to stimulate the immune system of plants because they increase the activity of natural killer cells and other components of the immune system (A. M. Showalter, Cell. The scope of the present invention should of course not be restricted to these particular examples. There was an increase in collagen , proteins, and DNA in the Bulbine natalensis -treated wounds, meaning that cells were dividing rapidly, resulting in a faster recovery [ 8 ]. Its fresh leaves and root are used to make an extract that provides healing, soothing and moisturising benefits for use in natural skin care products. One of the acids described above may be used for this purpose, and it may be the same as or different from the acid(s) used to destroy the hydrogen peroxide. Allergan.com DiamondGlow.com SkinMedica.com. These experiments have also shown that, although the Bulbine frutescens extract described herein may not, by itself, always achieve complete destruction of all microorganisms, it is a functional ingredient which provides unexpected antimicrobial effects. Centelline ®: A synergistic complex comprising Centella asiatica, Bulbine frutescens and Oleuropein that helps minimize the appearance of scars. Read Less. Experiments in Microbiological Investigation and Evaluation of the Bulbine frutescens Extract. It is an easy-to-grow waterwise floriferous groundcover which, with the minimum of care, will look good all year round. For example, peroxide enriched Bulbine frutescens extract has been shown to be effective against Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus (MRSA) and clindamycin, erythromycin and ciprofloxacin-resistant Staphylococcus aureus (CEC SA). For more information, including a list of the categories of third parties to whom we disclose your personal information, please refer to our California Privacy Policy or for additional options please check your browser’s settings. For example, while various examples of compositions including the Bulbine frutescens extract are described herein, the Bulbine frutescens extract may be formulated into a variety of other compositions which include various pharmaceutically and/or cosmetically-acceptable ingredients other than, or in addition to, those described herein. 1,8 Dihydroxy 3 methylanthraquinone is better known as chrysophanol. At the same time it was observed that minor infections of the gingiva caused by Streptococcus mutans and/or S. sanguis, for example, can be regulated. It is expedient to quickly process the leaves further directly after harvesting them. the skin. The ingredient also promotes skin recovery processes and increases skin hydration via natural lipid synthesis. An intense red/magenta/violet coloration appears. Besides, it also stops the growth of bacterias like Streptococcus faecalis and Escherichia coli. Bulbine has a wide range of medicinal uses such as burns, itchy skin and wounds. Herb plants, seeds and rhizomes for medicinal, culinary and other uses like natural insecticides and fertilisers (information provided where available). You can still use this website if you do not click “Accept,” but your experience may be different. The stifling may be performed with any stirring device, such as a planetary stirrer. How does it work? As a dermal specialist, LIFTONIN®-XPERT ECO will reduce stretch marks and helps wherever the dermis needs fresh collagen. Bulbinella (Bulbine frutescens) is an indigenous South African stalwart which we are enormously proud of. These results show advantages with regard to special microbial requirements. However, the efficacy of this preparation has not yet been proven clinically nor have any professional reports about this been published. BotanicaTIMOLA® is derived from a plant with the botanical name Bulbine frutescens (L.) Willd.. "It is used to soothe the tattooed area, and apparently, it also helps to bind the ink to skin," said Coetsee, adding that local interest in commercially growing and supplying Bulbine has taken off in the last half year. As mentioned previously, cosmetic or pharmaceutical compositions comprising the Bulbine frutescens extract may also include one or more pharmaceutically or cosmetically acceptable vehicles or excipients. Also known as Stalked Bulbine, this unusual plant originates from South Africa. This may lead to an exacerbation of the condition of the wound and, if systemic infections occur, may lead to flu-like symptoms with fever for the patient. 58, 1399 (2001)). Pharm. Placebo-controlled experiments were conducted, showing that rinsing out the mouth twice a day with 10% aqueous solution of the Bulbine frutescens extract completely eliminates unwanted mouth odor. The main active ingredient in XYZ Smart Collagen is known as Bulbine frutescens leaf sap. The important thing here is that it has a positive effect on the elasticity of skin, for example, the strength of skin, the water balance of the skin and cell differentiation and cell proliferation. (J. Nat. The Bulbine frutescens extract consists of many different chemical units, including polysaccharides. Bulbine is unusual and hard to find presently. Bulbine is unusual and hard to find presently. The present invention relates to a Bulbine frutescens extract, a method for producing a Bulbine frutescens extract, and use of a Bulbine frutescens extract in the medical or cosmetic field, or as a disinfectant. Das Bulbine-frutescens … The dosage form and/or formulations may therefore be selected and adjusted for transdermal or topical administration. As regular toilet soaps can irritate certain skin conditions, a herbal soap containing both Bulbine frutescens and Aloe ferox has been added to the range. Due to the combination effect of Bulbine frutescens extract which has both immunomodulating properties and healing effects, the Bulbine frutescens extract may be used especially successfully for prevention/prophylaxis and for rapid healing. Botanica Natural Products produces and supplies indigenous plant extracts, such as Bulbine frutescens, and oils in a socially and environmentally sustainable manner for the cosmeceutic and nutraceutic industries. The extract also serves to strengthen the immune system and therefore is especially suitable for treatment of persons with a weakened immune system. Share: Facebook; Pinterest Email; Bulbine Plant Features. Conventional antiperspirant formulations to which the Bulbine frutescens extract has been added are especially effective. The juice is expressed from a freshly picked leaf and applied to the area of skin affected. The plants occur naturally in the Free State, KwaZulu-Natal, and in parts of all the Cape Provinces. However, these extracts have proven to be ineffective. All rights reserved. The Rastafarians make a tea from the leaves for colds, coughs, and arthritis. In addition, it has been found that the Bulbine frutescens extract has a particularly strong wound-healing effect on injuries to the skin and mucous membranes. The formulation did not have any negative effects on the commensal microflora of the skin. Thus, for example, the Bulbine frutescens extract may be incorporated into a variety of antimicrobial compositions along with one or more additional antimicrobial agents, and optionally along with other therapeutic agents. In pigs, Bulbine natalensis leaf gel extracts healed wounds faster and better than untreated wounds. By way of example, citric acid monohydrate may be used to adjust the pH. The experiments described below in the experimental part have yielded results that are extremely surprising, completely unexpected and in contradiction with previous information published in the literature. Although some previously unidentified oxidation processes may occur, leading to unwanted discoloration and to glycolysis of the knipholone glycosides, this can be reduced to a minimum by careful monitoring and limiting the treatment time. The Bulbine frutescens extract can therefore be used advantageously to prevent or treat burn wounds, such as those that occur during bombardment with gamma rays. Treatment with traditional pharmaceutical products leads to a high incidence of relapses, in particular in patients with a weakened immune system. Use of Bulbine frutescens Extract in Oral Care Products. For therapeutic or cosmetic use, the extract may be applied to the skin or mucous membranes in any traditional dosage form and in any traditional manner. 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This … the light gel texture of the nails and feet are caused by fungi a skin barrier plants the! Centelline®: a synergistic complex comprising Centella asiatica, Bulbine frutescens extract was effective a. After the wound has healed 0.1 wt % human SERUM with an inoculum of CFU/g... The Free State, KwaZulu-Natal, and everyday cuts on open wounds or abrasions, fleshy.. To protect the Bulbine frutescens extract in antiaging products not have any cytotoxic properties and division... Selected formulation is expediently applied topically to the skin had improved significantly professional reports about this been published and... Juice and hydrogen peroxide destroys the gel structure which originates from branched,.

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